An intra-droplet particle switch for droplet microfluidics using bulk acoustic waves

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

To transfer cell- and bead-assays into droplet-based platforms typically requires the use of complex microfluidic circuits, which calls for methods to switch the direction of the encapsulated particles. We present a microfluidic chip where the combination of acoustic manipulation at two different harmonics and a trident-shaped dropletsplitter enables direction-switching of microbeads and yeast cells in droplet microfluidic circuits. At the first harmonic, the encapsulated particles exit the splitter in the center daughter droplets, while at the second harmonic, the particles exit in the side daughter droplets. This method holds promises for droplet-based assays where particle-positioning needs to be selectively controlled.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • Uppsala universitet
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci)
Originalspråkengelska
Artikelnummer031101
TidskriftBiomicrofluidics
Volym11
Utgåva nummer3
StatusPublished - 2017 maj 1
PublikationskategoriForskning
Peer review utfördJa

Relaterad forskningsoutput

Anna Fornell, 2018 jun 5, Lund: Department of Biomedical Engineering, Lund university. 134 s.

Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

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