Analysis of White Adipose Tissue Gene Expression Reveals CREB1 Pathway Altered in Huntington's Disease.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

In addition to classical neurological symptoms, Huntington's disease (HD) is complicated by peripheral pathology and both the mutant gene and the protein are found in cells and tissues throughout the body. Despite the adipose tissue gene expression alterations described in HD mouse models, adipose tissue and its gene expression signature have not been previously explored in human HD.

Detaljer

Författare
  • Andy McCourt
  • Jennifer Parker
  • Edina Silajdzic
  • Salman Haider
  • Huma Sethi
  • Sarah J Tabrizi
  • Thomas T Warner
  • Maria Björkqvist
Enheter & grupper
Externa organisationer
  • University College London
  • National Hospital for Neurology and Neurosurgery
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Neurovetenskaper
Originalspråkengelska
Sidor (från-till)371-382
TidskriftJournal of Huntington's disease
Volym4
Utgåva nummer4
StatusPublished - 2015
PublikationskategoriForskning
Peer review utfördJa

Nedladdningar

Ingen tillgänglig data

Relaterad forskningsoutput

Mccourt, A., 2016, Lund: Lund University: Faculty of Medicine. 80 s.

Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

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