Antiproliferative effects of curcumin analog L49H37 in pancreatic stellate cells: a comparative study.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Pancreatic cancer is a devastating disease with poor prognosis. It is characterized by a pronounced stromal reaction, which resists chemotherapeutics and effective tumor treatment. Pancreatic stellate cells (PSCs) are mainly responsible for this stromal reaction. Moreover, the cancer and stromal interaction seems to promote tumor proliferation. In this study, L49H37, a newly synthesized curcumin analog, was used as intervention to target the stromal compartment of pancreatic cancer.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Cancer och onkologi
Originalspråkengelska
Sidor (från-till)391-398
TidskriftAnnals of gastroenterology : quarterly publication of the Hellenic Society of Gastroenterology
Volym28
Utgåva nummer3
StatusPublished - 2015
PublikationskategoriForskning
Peer review utfördJa

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