Arynes in the Monoarylation of Unprotected Carbohydrate Amines

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

A CsF-mediated method has been developed for the N-arylation of amino sugars that affords good to excellent yields of arylated products under mild conditions involving the in situ generation of arynes. The reaction conditions tolerate a variety of common carbohydrate protecting groups and also performs exceptionally well on unprotected amino sugar derivatives. The reactions are scalable in moderate to good yields with broad scope.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • Lund University
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Organisk kemi
Originalspråkengelska
Sidor (från-till)616-619
Antal sidor4
TidskriftOrganic Letters
Volym20
Utgåva nummer3
StatusPublished - 2018 feb 2
PublikationskategoriForskning
Peer review utfördJa