Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Autofluorescence is a nuisance in the field of fluorescence imaging and tomography of exogenous molecular markers in tissue, degrading the quality of the collected data. In this letter, we report autofluorescence insensitive imaging using highly efficient upconverting nanocrystals (NaYF4: Yb3+ /Tm3+) in a tissue phantom illuminated with near- infrared radiation of 85 mW/cm(2). It was found that imaging with such nanocrystals leads to an exceptionally high contrast compared to traditional downconverting fluorophores due to the absence of autofluorescence. Upconverting nanocrystals may be envisaged as important biological markers for tissue imaging purposes. c 2008 American Institute of Physics. [DOI: 10.1063/1.3005588]

Detaljer

Författare
  • Can Xu
  • Niclas Svensson
  • Johan Axelsson
  • Pontus Svenmarker
  • Gabriel Somesfalean
  • Guanying Chen
  • Huijuan Liang
  • Haichun Liu
  • Zhiguo Zhang
  • Stefan Andersson-Engels
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Atom- och molekylfysik och optik
Originalspråkengelska
TidskriftApplied Physics Letters
Volym93
Utgåva nummer17
StatusPublished - 2008
PublikationskategoriForskning
Peer review utfördJa

Nedladdningar

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Relaterad forskningsoutput

Pontus Svenmarker, 2012, 201 s.

Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

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