Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media

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title = "Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media",
abstract = "Autofluorescence is a nuisance in the field of fluorescence imaging and tomography of exogenous molecular markers in tissue, degrading the quality of the collected data. In this letter, we report autofluorescence insensitive imaging using highly efficient upconverting nanocrystals (NaYF4: Yb3+ /Tm3+) in a tissue phantom illuminated with near- infrared radiation of 85 mW/cm(2). It was found that imaging with such nanocrystals leads to an exceptionally high contrast compared to traditional downconverting fluorophores due to the absence of autofluorescence. Upconverting nanocrystals may be envisaged as important biological markers for tissue imaging purposes. c 2008 American Institute of Physics. [DOI: 10.1063/1.3005588]",
author = "Can Xu and Niclas Svensson and Johan Axelsson and Pontus Svenmarker and Gabriel Somesfalean and Guanying Chen and Huijuan Liang and Haichun Liu and Zhiguo Zhang and Stefan Andersson-Engels",
year = "2008",
doi = "10.1063/1.3005588",
language = "English",
volume = "93",
journal = "Applied Physics Letters",
issn = "0003-6951",
publisher = "American Institute of Physics (AIP)",
number = "17",