Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media

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Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media. / Xu, Can; Svensson, Niclas; Axelsson, Johan; Svenmarker, Pontus; Somesfalean, Gabriel; Chen, Guanying; Liang, Huijuan; Liu, Haichun; Zhang, Zhiguo; Andersson-Engels, Stefan.

I: Applied Physics Letters, Vol. 93, Nr. 17, 2008.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Harvard

Xu, C, Svensson, N, Axelsson, J, Svenmarker, P, Somesfalean, G, Chen, G, Liang, H, Liu, H, Zhang, Z & Andersson-Engels, S 2008, 'Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media', Applied Physics Letters, vol. 93, nr. 17. https://doi.org/10.1063/1.3005588

APA

Xu, C., Svensson, N., Axelsson, J., Svenmarker, P., Somesfalean, G., Chen, G., Liang, H., Liu, H., Zhang, Z., & Andersson-Engels, S. (2008). Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media. Applied Physics Letters, 93(17). https://doi.org/10.1063/1.3005588

CBE

Xu C, Svensson N, Axelsson J, Svenmarker P, Somesfalean G, Chen G, Liang H, Liu H, Zhang Z, Andersson-Engels S. 2008. Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media. Applied Physics Letters. 93(17). https://doi.org/10.1063/1.3005588

MLA

Vancouver

Author

Xu, Can ; Svensson, Niclas ; Axelsson, Johan ; Svenmarker, Pontus ; Somesfalean, Gabriel ; Chen, Guanying ; Liang, Huijuan ; Liu, Haichun ; Zhang, Zhiguo ; Andersson-Engels, Stefan. / Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media. I: Applied Physics Letters. 2008 ; Vol. 93, Nr. 17.

RIS

TY - JOUR

T1 - Autofluorescence insensitive imaging using upconverting nanocrystals in scattering media

AU - Xu, Can

AU - Svensson, Niclas

AU - Axelsson, Johan

AU - Svenmarker, Pontus

AU - Somesfalean, Gabriel

AU - Chen, Guanying

AU - Liang, Huijuan

AU - Liu, Haichun

AU - Zhang, Zhiguo

AU - Andersson-Engels, Stefan

PY - 2008

Y1 - 2008

N2 - Autofluorescence is a nuisance in the field of fluorescence imaging and tomography of exogenous molecular markers in tissue, degrading the quality of the collected data. In this letter, we report autofluorescence insensitive imaging using highly efficient upconverting nanocrystals (NaYF4: Yb3+ /Tm3+) in a tissue phantom illuminated with near- infrared radiation of 85 mW/cm(2). It was found that imaging with such nanocrystals leads to an exceptionally high contrast compared to traditional downconverting fluorophores due to the absence of autofluorescence. Upconverting nanocrystals may be envisaged as important biological markers for tissue imaging purposes. c 2008 American Institute of Physics. [DOI: 10.1063/1.3005588]

AB - Autofluorescence is a nuisance in the field of fluorescence imaging and tomography of exogenous molecular markers in tissue, degrading the quality of the collected data. In this letter, we report autofluorescence insensitive imaging using highly efficient upconverting nanocrystals (NaYF4: Yb3+ /Tm3+) in a tissue phantom illuminated with near- infrared radiation of 85 mW/cm(2). It was found that imaging with such nanocrystals leads to an exceptionally high contrast compared to traditional downconverting fluorophores due to the absence of autofluorescence. Upconverting nanocrystals may be envisaged as important biological markers for tissue imaging purposes. c 2008 American Institute of Physics. [DOI: 10.1063/1.3005588]

U2 - 10.1063/1.3005588

DO - 10.1063/1.3005588

M3 - Article

VL - 93

JO - Applied Physics Letters

JF - Applied Physics Letters

SN - 0003-6951

IS - 17

ER -