B-1 Cells Carry the Memory of Neonatal Immune Imprinting

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B-1 Cells Carry the Memory of Neonatal Immune Imprinting. / Vergani, Stefano; Yuan, Joan.

I: Immunity, Vol. 53, Nr. 1, 2020, s. 11-13.

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TY - JOUR

T1 - B-1 Cells Carry the Memory of Neonatal Immune Imprinting

AU - Vergani, Stefano

AU - Yuan, Joan

PY - 2020

Y1 - 2020

N2 - Group A Streptococcus is a common pathogen that elicits a protective humoral response against the cell wall component GlcNAc. In this issue of Immunity, New et al. demonstrate the ability of long-lived B-1 cells to be programmed by microbial colonization and early life immunization to uniquely incorporate GlcNAc reactivity in mice, establishing their critical role in mediating neonatal immune imprinting.

AB - Group A Streptococcus is a common pathogen that elicits a protective humoral response against the cell wall component GlcNAc. In this issue of Immunity, New et al. demonstrate the ability of long-lived B-1 cells to be programmed by microbial colonization and early life immunization to uniquely incorporate GlcNAc reactivity in mice, establishing their critical role in mediating neonatal immune imprinting.

U2 - 10.1016/j.immuni.2020.06.018

DO - 10.1016/j.immuni.2020.06.018

M3 - Article

C2 - 32668222

AN - SCOPUS:85087791765

VL - 53

SP - 11

EP - 13

JO - Immunity

JF - Immunity

SN - 1074-7613

IS - 1

ER -