Bacterial Adherence and Epithelial Cell Cytokine Production

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Epithelial cell lines produce the cytokines IL-1α, IL-6 and IL-8 when stimulated with Escherichia coli. The cytokine response is enhanced by P fimbriae. The epithelial cell lines also respond to stimulation with other cytokines. These in vitro findings were confirmed in vivo in patients with E. coli infection who secreted IL-6 and IL-8 into the urine. The observations suggest that epithelial cells play a more active role in the mucosal immune response than previously recognized.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • Lund University
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Immunologi inom det medicinska området
Originalspråkengelska
Sidor (från-till)359-364
Antal sidor6
TidskriftZentralblatt fur Bakteriologie
Volym278
Utgåva nummer2-3
StatusPublished - 1993 jan 1
PublikationskategoriForskning
Peer review utfördJa