Base-catalyzed intramolecular condensation of tokinolide B.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

The novel pentacyclic compound cyclotokinolide B was obtained from the natural phthalide tokinolide B under basic conditions, via the chemoselective -enol lactone opening followed by a Michael addition of the generated carbanion to the enone and subsequent equilibration. This result confirms that some dimeric phthalides undergo intramolecular cyclizations in basic media.

Detaljer

Författare
  • B Quiroz-García
  • L Hernández
  • R A Toscano
  • Olov Sterner
  • G Delgado
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Organisk kemi
Originalspråkengelska
Sidor (från-till)2509-2512
TidskriftTetrahedron Letters
Volym44
Utgivningsnummer12
StatusPublished - 2003
PublikationskategoriForskning
Peer review utfördJa