Biomaterials at the interface of nano- and micro-scale vector-cellular interactions in genetic vaccine design

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift


The development of safe and effective vaccines for the prevention of elusive infectious diseases remains a public health priority. Immunization, characterized by adaptive immune responses to specific antigens, can be raised by an array of delivery vectors. However, current commercial vaccination strategies are predicated on the retooling of archaic technology. This review will discuss current and emerging strategies designed to elicit immune responses in the context of genetic vaccination. Selected strategies at the biomaterial-biological interface will be emphasized to illustrate the potential of coupling both fields towards a common goal.


Externa organisationer
  • University at Buffalo
Sidor (från-till)8053-8068
TidskriftJournal of Materials Chemistry. B
StatusPublished - 2014
Peer review utfördJa
Externt publiceradJa