Biomaterials at the interface of nano- and micro-scale vector-cellular interactions in genetic vaccine design

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

The development of safe and effective vaccines for the prevention of elusive infectious diseases remains a public health priority. Immunization, characterized by adaptive immune responses to specific antigens, can be raised by an array of delivery vectors. However, current commercial vaccination strategies are predicated on the retooling of archaic technology. This review will discuss current and emerging strategies designed to elicit immune responses in the context of genetic vaccination. Selected strategies at the biomaterial-biological interface will be emphasized to illustrate the potential of coupling both fields towards a common goal.

Detaljer

Författare
Externa organisationer
  • University at Buffalo
Originalspråkengelska
Sidor (från-till)8053-8068
TidskriftJournal of Materials Chemistry. B
Volym46
StatusPublished - 2014
PublikationskategoriForskning
Peer review utfördJa
Externt publiceradJa