Capsaicin enhances allergic contact dermatitis in guinea pig.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Guinea pigs were sensitized to dinitrochlorobenzene (DNCB) by the intracutaneous route and challenged epicutaneously tin the flanks. The intensity of the allergic contact dermatitis was evaluated by inspection and palpation as well us by wet weight determination. With the purpose of diminishing tissue neuropeptides, and substance P in particular, the animals were treated with capsaicin either between induction and challenge, or before sensitization, In comparison with controls, the contact dermatitis was Enhanced in both groups of animals treated with capsaicin.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • Lund University
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Dermatologi och venereologi
Originalspråkengelska
Sidor (från-till)30-34
TidskriftContact Dermatitis
Volym24
Utgåva nummer1
StatusPublished - 1991
PublikationskategoriForskning
Peer review utfördJa