C-band heteromorphism in breast cancer patients

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

The pattern of heteromorphism in the C-band-positive constitutive heterochromatin of human chromosomes #1, #9, and #16 was studied in peripheral lymphocytes of 54 breast cancer patients and 78 control individuals. The parameters of the heterochromatic regions analyzed were relative size, symmetry-asymmetry within homologous pairs, and prevalence of inversions. Significant differences between the two groups were found in C-band size of chromosomes #1, #9, and #16 and in incidence of inversions on chromosomes #1 and #9. Significant differences were noted between premenopausal and postmenopausal cancer patients in regard to inversions on chromosome #9 and between familial and sporadic patients in regard to C-band size on chromosome #16.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • Saint-Louis Hospital, Paris
  • Skåne University Hospital
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Cancer och onkologi
Originalspråkengelska
Sidor (från-till)37-42
Antal sidor6
TidskriftCancer Genetics and Cytogenetics
Volym18
Utgivningsnummer1
StatusPublished - 1985 jan 1
PublikationskategoriForskning
Peer review utfördJa