Cerebral Microbleeds and White Matter Hyperintensities in Cognitively Healthy Elderly: A Cross-Sectional Cohort Study Evaluating the Effect of Arterial Stiffness.

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T1 - Cerebral Microbleeds and White Matter Hyperintensities in Cognitively Healthy Elderly: A Cross-Sectional Cohort Study Evaluating the Effect of Arterial Stiffness.

AU - Gustavsson, Anna-Märta

AU - Stomrud, Erik

AU - Abul-Kasim, Kasim

AU - Minthon, Lennart

AU - Nilsson, Peter

AU - Hansson, Oskar

AU - Nägga, Katarina

PY - 2015

Y1 - 2015

N2 - Arterial stiffness reflects the ageing processes in the vascular system, and studies have shown an association between reduced cognitive function and cerebral small vessel disease. Small vessel disease can be visualized as white matter hyperintensities (WMH) and lacunar infarcts but also as cerebral microbleeds on brain magnetic resonance imaging (MRI). We aimed to investigate if arterial stiffness influences the presence of microbleeds, WMH and cognitive function in a population of cognitively healthy elderly.

AB - Arterial stiffness reflects the ageing processes in the vascular system, and studies have shown an association between reduced cognitive function and cerebral small vessel disease. Small vessel disease can be visualized as white matter hyperintensities (WMH) and lacunar infarcts but also as cerebral microbleeds on brain magnetic resonance imaging (MRI). We aimed to investigate if arterial stiffness influences the presence of microbleeds, WMH and cognitive function in a population of cognitively healthy elderly.

U2 - 10.1159/000377710

DO - 10.1159/000377710

M3 - Article

VL - 5

SP - 41

EP - 51

JO - Cerebrovascular Diseases Extra

T2 - Cerebrovascular Diseases Extra

JF - Cerebrovascular Diseases Extra

SN - 1664-5456

IS - 2

ER -