Ceruloplasmin and atrial fibrillation: evidence of causality from a population-based Mendelian randomization study.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Inflammatory diseases and inflammatory markers secreted by the liver, including C-reactive protein (CRP) and ceruloplasmin, have been associated with incident atrial fibrillation (AF). Genetic studies have not supported a causal relationship between CRP and AF, but the relationship between ceruloplasmin and AF has not been studied. The purpose of this Mendelian randomization study was to explore whether genetic polymorphisms in the gene encoding ceruloplasmin are associated with elevated ceruloplasmin levels, and whether such genetic polymorphisms are also associated with the incidence of AF.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Kardiologi
Originalspråkengelska
Sidor (från-till)164-171
TidskriftJournal of Internal Medicine
Volym275
Utgåva nummer2
StatusPublished - 2014
PublikationskategoriForskning
Peer review utfördJa

Relaterad forskningsoutput

Samuel Adamsson Eryd, 2015, Department of Clinical Sciences, Lund University. 140 s.

Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

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