Clinical algorithms to aid osteoarthritis guideline dissemination

Forskningsoutput: TidskriftsbidragÖversiktsartikel


Background: Numerous scientific organisations have developed evidence-based recommendations aiming to optimise the management of osteoarthritis (OA). Uptake, however, has been suboptimal. The purpose of this exercise was to harmonize the recent recommendations and develop a user-friendly treatment algorithm to facilitate translation of evidence into practice. Methods: We updated a previous systematic review on clinical practice guidelines (CPGs) for OA management. The guidelines were assessed using the Appraisal of Guidelines for Research and Evaluation for quality and the standards for developing trustworthy CPGs as established by the National Academy of Medicine (NAM). Four case scenarios and algorithms were developed by consensus of a multidisciplinary panel. Results: Sixteen guidelines were included in the systematic review. Most recommendations were directed toward physicians and allied health professionals, and most had multi-disciplinary input. Analysis for trustworthiness suggests that many guidelines still present a lack of transparency. A treatment algorithm was developed for each case scenario advised by recommendations from guidelines and based on panel consensus. Conclusion: Strategies to facilitate the implementation of guidelines in clinical practice are necessary. The algorithms proposed are examples of how to apply recommendations in the clinical context, helping the clinician to visualise the patient flow and timing of different treatment modalities.


  • S. R F Meneses
  • A. P. Goode
  • A. E. Nelson
  • J. Lin
  • J. M. Jordan
  • K. D. Allen
  • K. L. Bennell
  • L. S. Lohmander
  • L. Fernandes
  • M. C. Hochberg
  • M. Underwood
  • P. G. Conaghan
  • S. Liu
  • T. E. McAlindon
  • Y. M. Golightly
  • D. J. Hunter
Enheter & grupper
Externa organisationer
  • Kolling Institute of Medical Research
  • Duke University
  • University of North Carolina
  • Peking University
  • University of Melbourne
  • Odense University Hospital
  • Slotervaart Hospital
  • University of Warwick
  • University of Leeds
  • Tufts Medical Center

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Ortopedi
  • Reumatologi och inflammation


Sidor (från-till)1487-1499
TidskriftOsteoarthritis and Cartilage
Utgåva nummer9
Tidigt onlinedatum2016 apr 15
StatusPublished - 2016 sep
Peer review utfördJa


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