Coffee and tea consumption and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

The epidemiological evidence regarding the association of coffee and tea consumption with prostate cancer risk is inconclusive, and few cohort studies have assessed these associations by disease stage and grade. We examined the associations of coffee (total, caffeinated and decaffeinated) and tea intake with prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition. Among 142,196 men, 7,036 incident prostate cancer cases were diagnosed over 14 years of follow-up. Data on coffee and tea consumption were collected through validated country-specific food questionnaires at baseline. We used Cox proportional hazards regression models to compute hazard ratios (HRs) and 95% confidence intervals (CI). Models were stratified by center and age, and adjusted for anthropometric, lifestyle and dietary factors. Median coffee and tea intake were 375 and 106 mL/day, respectively, but large variations existed by country. Comparing the highest (median of 855 mL/day) versus lowest (median of 103 mL/day) consumers of coffee and tea (450 vs. 12 mL/day) the HRs were 1.02 (95% CI, 0.94–1.09) and 0.98 (95% CI, 0.90–1.07) for risk of total prostate cancer and 0.97 (95% CI, 0.79–1.21) and 0.89 (95% CI, 0.70–1.13) for risk of fatal disease, respectively. No evidence of association was seen for consumption of total, caffeinated or decaffeinated coffee or tea and risk of total prostate cancer or cancer by stage, grade or fatality in this large cohort. Further investigations are needed to clarify whether an association exists by different preparations or by concentrations and constituents of these beverages.

Detaljer

Författare
  • Abhijit Sen
  • Nikos Papadimitriou
  • Pagona Lagiou
  • Aurora Perez-Cornago
  • Ruth C. Travis
  • Timothy J. Key
  • Neil Murphy
  • Marc Gunter
  • Heinz Freisling
  • Ioanna Tzoulaki
  • David C. Muller
  • Amanda J. Cross
  • David S. Lopez
  • Manuela Bergmann
  • Heiner Boeing
  • Christina Bamia
  • Anastasia Kotanidou
  • Anna Karakatsani
  • Anne Tjønneland
  • Cecilie Kyrø
  • Malene Outzen
  • María Luisa Redondo
  • Valerie Cayssials
  • Maria Dolores Chirlaque
  • Aurelio Barricarte
  • Maria Jose Sánchez
  • Nerea Larrañaga
  • Rosario Tumino
  • Sara Grioni
  • Domenico Palli
  • Saverio Caini
  • Carlotta Sacerdote
  • Bas Bueno-de-Mesquita
  • Tilman Kühn
  • Rudolf Kaaks
  • Lena Maria Nilsson
  • Rikard Landberg
  • Bodil Hammer Bech
  • Kim Overvad
  • Dagfinn Aune
  • Kay Tee Khaw
  • Elio Riboli
  • Dimitrios Trichopoulos
  • Antonia Trichopoulou
  • Konstantinos K. Tsilidis
Enheter & grupper
Externa organisationer
  • Norwegian University of Science and Technology
  • University of Ioannina
  • National and Kapodistrian University of Athens
  • Harvard University
  • University of Oxford
  • International Agency for Research on Cancer, World Health Organization
  • Imperial College London
  • University of Texas
  • University of Texas Health Science Center at Houston
  • German Institute of Human Nutrition
  • Hellenic Health Foundation, Athens
  • Danish Cancer Society Research Center
  • Public Health Directorate
  • Bellvitge Biomedical Research Institute
  • Murcia Regional Health Council
  • University of Murcia
  • Health Research Institute of Navarra (IDISNA)
  • Civic and M.P.Arezzo Hospital
  • Istituto Nazionale dei Tumori
  • Cancer Research and Prevention Institute
  • Citta' della Salute e della Scienza Hospital-University of Turin
  • National Institute for Public Health and the Environment (RIVM)
  • University Medical Center Utrecht
  • University of Malaya
  • German Cancer Research Centre
  • Umeå University
  • Chalmers University of Technology
  • Aarhus University
  • Bjørknes University College
  • University of Cambridge
  • CIBER Epidemiology and Public Health (CIBERESP)
  • Public Health Division of Gipuzkoa
  • Evangelismos Athens General Hospital
  • Attikon University Hospital
  • University of Granada
  • Hospital Clínico Universitario San Cecilio
  • Centre for Cancer Epidemiology and Prevention (CPO Piemonte)
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Cancer och onkologi
  • Näringslära

Nyckelord

Originalspråkengelska
Sidor (från-till)240-250
TidskriftInternational Journal of Cancer
Volym144
Utgivningsnummer2
Tidigt onlinedatum2018 jun 26
StatusPublished - 2019
PublikationskategoriForskning
Peer review utfördJa