Concomitant contact dermatitis due to textile dyes and to colour film developers can be explained by the formation of the same hapten

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Concomitant contact dermatitis due to textile dyes and to colour film developers can be explained by the formation of the same hapten. / Hansson, Christer; Ahlfors, Stefan; Bergendorff, Ola.

I: Contact Dermatitis, Vol. 37, Nr. 1, 1997, s. 27-31.

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T1 - Concomitant contact dermatitis due to textile dyes and to colour film developers can be explained by the formation of the same hapten

AU - Hansson, Christer

AU - Ahlfors, Stefan

AU - Bergendorff, Ola

PY - 1997

Y1 - 1997

N2 - p-phenylenediamine derivatives are widely used in industry and in cosmetics, and several of them are well-known sensitizers. One group of allergenic p-phenylenediamine derivatives are used as colour film developers. Cross-reactivity between the colour film developers has been reported. In this paper, an occupational facial dermatitis due to colour film developers is described. The patient reacted to colour film developers (CD-1, CD-2, CD-3, and CD-4), but not to other p-phenylenediamine derivatives tested. He also showed allergic reactions to Disperse Blue 106 and Disperse Blue 124 and to Disperse Red 17, but not to Disperse Orange 3. The activation of the colour film developers by oxidation at physiological pH was analysed with chemical methods, and the mechanism responsible for the concomitant reactivities to the colour film developers and the disperse dyes at a molecular level is discussed.

AB - p-phenylenediamine derivatives are widely used in industry and in cosmetics, and several of them are well-known sensitizers. One group of allergenic p-phenylenediamine derivatives are used as colour film developers. Cross-reactivity between the colour film developers has been reported. In this paper, an occupational facial dermatitis due to colour film developers is described. The patient reacted to colour film developers (CD-1, CD-2, CD-3, and CD-4), but not to other p-phenylenediamine derivatives tested. He also showed allergic reactions to Disperse Blue 106 and Disperse Blue 124 and to Disperse Red 17, but not to Disperse Orange 3. The activation of the colour film developers by oxidation at physiological pH was analysed with chemical methods, and the mechanism responsible for the concomitant reactivities to the colour film developers and the disperse dyes at a molecular level is discussed.

KW - phenylenediamine PPD

KW - azo dye

KW - Disperse Blue 106

KW - Disperse Blue 124 Disperse Red 17

KW - Disperse Orange 3

KW - benzoquinone

KW - imine

KW - dermatitis

KW - cross-reactivity

KW - skin test

KW - cyclic voltametry

KW - colour film developer

U2 - 10.1111/j.1600-0536.1997.tb00370.x

DO - 10.1111/j.1600-0536.1997.tb00370.x

M3 - Article

VL - 37

SP - 27

EP - 31

JO - Contact Dermatitis

JF - Contact Dermatitis

SN - 0105-1873

IS - 1

ER -