Cracking the Sugar Code by Mass Spectrometry: An Invited Perspective in Honor of Dr. Catherine E. Costello, Recipient of the 2017 ASMS Distinguished Contribution Award

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Cracking the Sugar Code by Mass Spectrometry : An Invited Perspective in Honor of Dr. Catherine E. Costello, Recipient of the 2017 ASMS Distinguished Contribution Award. / Mirgorodskaya, Ekaterina; Karlsson, Niclas G.; Sihlbom, Carina; Larson, Göran; Nilsson, Carol L.

I: Journal of the American Society for Mass Spectrometry, Vol. 29, Nr. 6, 01.06.2018, s. 1065-1074.

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TY - JOUR

T1 - Cracking the Sugar Code by Mass Spectrometry

T2 - An Invited Perspective in Honor of Dr. Catherine E. Costello, Recipient of the 2017 ASMS Distinguished Contribution Award

AU - Mirgorodskaya, Ekaterina

AU - Karlsson, Niclas G.

AU - Sihlbom, Carina

AU - Larson, Göran

AU - Nilsson, Carol L.

PY - 2018/6/1

Y1 - 2018/6/1

N2 - The structural study of glycans and glycoconjugates is essential to assign their roles in homeostasis, health, and disease. Once dominated by nuclear magnetic resonance spectroscopy, mass spectrometric methods have become the preferred toolbox for the determination of glycan structures at high sensitivity. The patterns of such structures in different cellular states now allow us to interpret the sugar codes in health and disease, based on structure-function relationships. Dr. Catherine E. Costello was the 2017 recipient of the American Society for Mass Spectrometry’s Distinguished Contribution Award. In this Perspective article, we describe her seminal work in a historical and geographical context and review the impact of her research accomplishments in the field. 8[Figure not available: see fulltext.].

AB - The structural study of glycans and glycoconjugates is essential to assign their roles in homeostasis, health, and disease. Once dominated by nuclear magnetic resonance spectroscopy, mass spectrometric methods have become the preferred toolbox for the determination of glycan structures at high sensitivity. The patterns of such structures in different cellular states now allow us to interpret the sugar codes in health and disease, based on structure-function relationships. Dr. Catherine E. Costello was the 2017 recipient of the American Society for Mass Spectrometry’s Distinguished Contribution Award. In this Perspective article, we describe her seminal work in a historical and geographical context and review the impact of her research accomplishments in the field. 8[Figure not available: see fulltext.].

KW - Glycan mass spectrometry

KW - History of mass spectrometry

KW - Review

KW - Structural mass spectrometry

UR - http://www.scopus.com/inward/record.url?scp=85048678709&partnerID=8YFLogxK

U2 - 10.1007/s13361-018-1912-3

DO - 10.1007/s13361-018-1912-3

M3 - Article

C2 - 29644549

AN - SCOPUS:85048678709

VL - 29

SP - 1065

EP - 1074

JO - Journal of the American Society for Mass Spectrometry

JF - Journal of the American Society for Mass Spectrometry

SN - 1879-1123

IS - 6

ER -