Critical appraisal of the International Prophylaxis Study Group magnetic resonance image scale for evaluating haemophilic arthropathy

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A goal of the International Prophylaxis Study Group (IPSG) is to provide an accurate instrument to measure MRI-based disease severity of haemophilic arthropathy at various time points, so that longitudinal changes in disease severity can be identified to support decisions on treatment management. We review and discuss in this paper the evaluative purpose of the IPSG MRI scale in relation to its development and validation processes so far. We also critically appraise the validity, reliability and responsiveness of using the IPSG MRI scale in different clinical and research settings, and whenever applicable, compare these clinimetric properties of the IPSG MRI scale with those of its precursors, the compatible additive and progressive MRI scales.


  • Mirkamal Tolend
  • Haris Majeed
  • Magdy Soliman
  • Paulo Daruge
  • Marcelo Bordalo-Rodrigues
  • Sergio San Juan Dertkigil
  • Sridhar Gibikote
  • Shyamkumar N. Keshava
  • Jennifer Stimec
  • Amy Dunn
  • Ying Jia Li
  • Victor Blanchette
  • Björn Lundin
  • Andrea S. Doria
Enheter & grupper
Externa organisationer
  • Hospital for Sick Children, Toronto
  • University of São Paulo
  • University of Campinas
  • Christian Medical College & Hospital
  • University of Toronto
  • Skåne University Hospital
  • Ohio State University
  • Nanfang Hospital Hospital

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Medicinsk bildbehandling


StatusE-pub ahead of print - 2020
Peer review utfördJa