Cryo-TEM studies of DNA and DNA-lipid structures

Forskningsoutput: TidskriftsbidragÖversiktsartikel

Abstract

Studies published between 2001 and 2005 that utilise cryogenic transmission electron microscopy as a tool for investigating solutions containing DNA with or without amphiphiles present are reviewed. DNA or oligonucleotides form complexes with amphiphilic molecules such as lipids, so-called lipoplexes, and the structures and morphologies are excellent objects to study by cryogenic transmission electron microscopy. Recent studies show that this technique is in effective tool for identification of a range of structures such as unilamellar or multilamellar vesicles or dispersed liquid crystalline phases. (c) 2005 Elsevier Ltd. All rights reserved.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Fysikalisk kemi
Originalspråkengelska
Sidor (från-till)269-273
TidskriftCurrent Opinion in Colloid & Interface Science
Volym10
Utgåva nummer5-6
StatusPublished - 2005
PublikationskategoriForskning
Peer review utfördJa