Crystallization and preliminary X-ray diffraction of Trypanosoma cruzi dUTPase

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Crystals of Trypanosoma cruzi dUTPase have been grown. Two different morphologies are observed, depending on the molecular weight of the PEG used as precipitating agent in the mother liquor, both having a hexagonal unit cell with similar dimensions. Complete X-ray diffraction data have been collected to low resolution for one of the forms. The space group is P6322, with unit-cell dimensions a = 134.15, c = 147.05 Å. Peaks in the self-rotation function and the solvent content are consistent with two molecules of dUTPase per asymmetric unit.

Detaljer

Författare
  • V Bernier-Villamor
  • A Camacho
  • D Gonazález-Pacanowska
  • Eila Cedergren
  • A Antson
  • K S Wilson
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Strukturbiologi
Originalspråkengelska
Sidor (från-till)528-530
TidskriftActa Crystallographica. Section D: Biological Crystallography
VolymD55
StatusPublished - 1999
PublikationskategoriForskning
Peer review utfördJa