CSF neurofilament light differs in neurodegenerative diseases and predicts severity and survival.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

We hypothesized that CSF neurofilament light (NFL) levels would be elevated in dementias with subcortical involvement, including vascular dementia (VaD), but less elevated in dementias primarily affecting gray matter structures, such as Alzheimer disease (AD), and that elevated CSF NFL would correlate with disease severity and shorter survival time irrespective of clinical diagnosis.

Detaljer

Författare
  • Tobias Skillbäck
  • Bahman Farahmand
  • Jonathan W Bartlett
  • Christoffer Rosén
  • Niklas Mattsson
  • Katarina Nägga
  • Lena Kilander
  • Dorota Religa
  • Anders Wimo
  • Bengt Winblad
  • Lars Rosengren
  • Jonathan M Schott
  • Kaj Blennow
  • Maria Eriksdotter
  • Henrik Zetterberg
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Neurologi
Originalspråkengelska
Sidor (från-till)1945-1953
TidskriftNeurology
Volym83
Utgåva nummer21
StatusPublished - 2014
PublikationskategoriForskning
Peer review utfördJa