Cutaneous human papillomavirus 88: Remarkable differences in viral load.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

A human papillomavirus (HPV) was cloned from a patient with multiple squamous cell carcinomas (SCCs) and identified as HPV88, recently categorized into a new species within the genus Gamma. The HPV88 viral load in an SCC of the index patient exceeded 1 million copies/cell. By contrast, a survey of 447 skin lesions (79 actinic keratoses, 73 seborrhoeic keratoses, 169 basal cell carcinomas and 126 SCCs) and 362 healthy skin biopsies found detectable HPV88 DNA in only 7 specimens. All these had very low viral loads (<1 copy/10(3) cells) implying extreme biological variability in viral load.

Detaljer

Författare
  • Johanna Ekström
  • Alessandra Handisurya
  • Ola Forslund
  • Alexandra Geusau
  • Reinhard Kirnbauer
  • Joakim Dillner
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Cancer och onkologi
Originalspråkengelska
Sidor (från-till)477-480
TidskriftInternational Journal of Cancer
Volym122
Utgåva nummer2
StatusPublished - 2008
PublikationskategoriForskning
Peer review utfördJa

Relaterad forskningsoutput

Johanna Ekström, 2011, Avd för medicinsk mikrobiologi. 104 s.

Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

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