Detection and possible functional influence of antibodies directed againt the pancreatic islet cell surface.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Antibodies directed towards determinants on the surface of rat islet cells can be detected qualitatively by the indirect immunofluorescence or quantitatively by a specific radioassay for IgG. Antibodies are found in insulin-dependent diabetics or in rabbits immunized with islet cells. Such antibodies may affect the B-cell function as indicated by the inhibition of incorporation of radioactive leucine into proinsulin/insulin in vitro.

Detaljer

Författare
Externa organisationer
  • Lund University
Originalspråkengelska
Sidor (från-till)157-163
Antal sidor7
TidskriftAdvances in Experimental Medicine and Biology
Volym119
StatusPublished - 1979 jan 1
PublikationskategoriForskning
Peer review utfördJa
Externt publiceradJa