Developing chicken oligodendrocytes express the type IV oligodendrocyte marker T4-O in situ, but not in vitro

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Bibtex

@article{282f09838fc6442f90e739ac415d5cb6,
title = "Developing chicken oligodendrocytes express the type IV oligodendrocyte marker T4-O in situ, but not in vitro",
abstract = "Accumulating data suggest that the oligodendrocyte population includes morphological and biochemical subtypes. We recently reported that a polyclonal antiserum against an unknown antigen, the T4-O molecule, labels a subpopulation of chicken oligodendrocytes, obviously representing the type IV variety of Del Rio Hortega. The present study examines the developmental expression of the T4-O molecule in situ and in vitro. The results show that T4-O immunoreactive cells first appear at E15 in the ventral funiculus. But, oligodendrocytes cultured in vitro with or without neurones do not develop a T4-O immunoreactivity. We conclude that oligodendrocytes in the spinal cord of chicken embryos first express the T4-O molecule some time after onset of myelination, and that the T4-O immunoreactive phenotype does not develop in vitro.",
keywords = "Cell culture, T4-O, Myelination, Development, White matter, Spinal cord, Oligodendrocyte, Chicken",
author = "Anderson, {Emma S} and Carl Bjartmar and {Eriksson Linsmeier}, Cecilia and Gunilla Westermark and Claes Hildebrand",
year = "2000",
doi = "10.1016/S0304-3940(00)00989-7",
language = "English",
volume = "284",
pages = "21--24",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier",
number = "1-2",

}