Diagnosis and treatment of brain metastases from solid tumors: Guidelines from the European Association of neuro-oncology (EANO)

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The management of patients with brain metastases has become a major issue due to the increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014, the European Association of Neuro-Oncology (EANO) created a multidisciplinary Task Force to draw evidence-based guidelines for patients with brain metastases from solid tumors. Here, we present these guidelines, which provide a consensus review of evidence and recommendations for diagnosis by neuroimaging and neuropathology, staging, prognostic factors, and different treatment options. Specifically, we addressed options such as surgery, stereotactic radiosurgery/stereotactic fractionated radiotherapy, whole-brain radiotherapy, chemotherapy and targeted therapy (with particular attention to brain metastases from non-small cell lung cancer, melanoma and breast and renal cancer), and supportive care.


  • Riccardo Soffietti
  • Ufuk Abacioglu
  • Brigitta Baumert
  • Stephanie E. Combs
  • Sara Kinhult
  • Johan M. Kros
  • Christine Marosi
  • Philippe Metellus
  • Alexander Radbruch
  • Salvador S.Villa Freixa
  • Michael Brada
  • Carmine M. Carapella
  • Matthias Preusser
  • Emilie Le Rhun
  • Roberta Rudà
  • Joerg C. Tonn
  • Damien C. Weber
  • Michael Weller
Externa organisationer
  • Skåne University Hospital

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Cancer och onkologi


Sidor (från-till)162-174
Antal sidor13
Utgåva nummer2
StatusPublished - 2017
Peer review utfördJa
Externt publiceradJa