Diffuse reflectance spectroscopy of liver tissue

Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKonferenspaper i proceeding

Abstract

Diffuse reflectance spectroscopy (DRS) with a fiber-optic contact probe is a cost-effective, rapid, and non-invasive optical method used to extract diagnosis information of tissue. By combining commercially available VIS- and NIR-spectrometers with various fiber-optic contact-probes, we have access to the full wavelength range from around 400 to 1600 nm. Using this flexible and portable spectroscopy system, we have acquired ex-vivo DRS-spectra from murine, porcine, and human liver tissue. For extracting the tissue optical properties from the measured spectra, we have employed and compared predictions from two models for light propagation in tissue, diffusion theory model (DT) and Monte Carlo simulations (MC).
The focus in this work is on the capacity of this DRS-technique in discriminating metastatic tumor tissue from normal liver tissue as well as in assessing and characterizing damage to non-malignant liver tissue induced by preoperative chemotherapy for colorectal liver metastases.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Teknisk mekanik
  • Atom- och molekylfysik och optik

Nyckelord

Originalspråkengelska
Titel på värdpublikation[Host publication title missing]
FörlagSPIE
Sidor95314E
Antal sidor10
Volym9531
StatusPublished - 2015
PublikationskategoriForskning
Peer review utfördJa
EvenemangSPIE Biophotonics South America 2015 - Rio de Janeiro, Brasilien
Varaktighet: 2015 maj 232015 maj 25

Publikationsserier

Namn
Volym9531
ISSN (tryckt)1996-756X
ISSN (elektroniskt)0277-786X

Konferens

KonferensSPIE Biophotonics South America 2015
LandBrasilien
OrtRio de Janeiro
Period2015/05/232015/05/25