DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Insulin secretion is enhanced upon the binding of Glucagon-like peptide-1 (GLP-1) to its receptor (GLP1R) in pancreatic β cells. Although a reduced expression of GLP1R in pancreatic islets from type 2 diabetic patients and hyperglycaemic rats has been established, it is still unknown if this is caused by differential DNA methylation of GLP1R in pancreatic islets of type 2 diabetic patients.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Medicinsk genetik
Originalspråkengelska
Artikelnummer76
TidskriftBMC Medical Genetics
Volym14
UtgivningsnummerJul,23
StatusPublished - 2013
PublikationskategoriForskning
Peer review utfördJa

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Relaterad forskningsoutput

Hall, E., 2015, Epigenetics and Diabetes. 59 s.

Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

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