Does next-generation sequencing of cyst fluid improve management of pancreatic cystic neoplasms?

Forskningsoutput: TidskriftsbidragÖversiktsartikel

Abstract

Pancreatic cystic lesions represent a heterogeneous group of diseases ranging from benign to malignant lesions. They are increasingly being detected due to the widespread use of cross-sectional imaging. Their management is a challenge because it is often not possible to reliably discriminate between malignant and nonmalignant lesions using current imaging technology. Next-generation sequencing (NGS) has the ability of both whole genome and targeted sequencing at a low cost and from a limited amount of DNA. NGS of cyst fluid aspired by endoscopic ultrasonography-guided fine-needle aspiration provides a valuable tool in biomarker research and may in the future help improve diagnosis and management of pancreatic cystic lesions.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • Skåne University Hospital
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Bioinformatik och systembiologi

Nyckelord

Originalspråkengelska
Sidor (från-till)1049-1051
Antal sidor3
TidskriftScandinavian Journal of Gastroenterology
Volym52
Utgivningsnummer10
StatusPublished - 2017 okt 3
PublikationskategoriForskning
Peer review utfördJa