Effect of nanoparticle size and magnetic field strength on the displacement signal in magnetomotive ultrasound imaging

Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKonferenspaper i proceeding

Abstract

Magnetomotive ultrasound imaging is an emerging technique where superparamagnetic iron oxide nanoparticles can be used as an ultrasound contrast agent. A time-varying external magnetic field acts to move tissue embedded particles, and ultrasound is used to detect the resulting tissue movement. In this experimental phantom study we observed a variation in the magnetomotive response in respect to physical size of the embedded superparamagnetic iron oxide nanoparticles. Given the same Fe concentration a weaker response, by a factor of 2, was detected with the larger nanoparticles. However, approximately seven times larger response remains, given the volume ratio between particles, implying a seven times larger response per binding event. We hypothesize that this can have bearing in molecular imaging.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • Skåne University Hospital
  • Genovis AB
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Radiologi och bildbehandling

Nyckelord

Originalspråkengelska
Titel på värdpublikation2016 IEEE International Ultrasonics Symposium, IUS 2016
FörlagIEEE Computer Society
Volym2016-November
ISBN (elektroniskt)9781467398978
StatusPublished - 2016 nov 1
PublikationskategoriForskning
Peer review utfördJa
Evenemang2016 IEEE International Ultrasonics Symposium, IUS 2016 - Tours, Frankrike
Varaktighet: 2016 sep 182016 sep 21

Konferens

Konferens2016 IEEE International Ultrasonics Symposium, IUS 2016
LandFrankrike
OrtTours
Period2016/09/182016/09/21