Effect of two kinds of pectin and guar gum on 1,2-dimethylhydrazine initiation of colon tumors and on fecal beta-glucuronidase activity in the rat

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

The effect of 5% low-methoxylated pectin, high-methoxylated pectin, and guar gum on 1,2-dimethylhydrazine initiation of colon cancer was investigated using groups of 30 rats. The growth of the rats in the different groups was very similar to that of control group fed a fiber-free diet. Both kinds of pectin increased the multiplicity of color tumors, whereas guar gum did not significantly influence carcinogenesis. Bacterial beta-glucuronidase activity in feces and colonic content was the same in pectin-fed rats and controls but significantly lower in the guar gum group. Thus, it was not related to the number of tumors in each group.

Detaljer

Författare
  • H G Bauer
  • N G Asp
  • A Dahlqvist
  • P E Fredlund
  • M Nyman
  • R Oste
Enheter & grupper
Externa organisationer
  • Skåne University Hospital
  • Lund University, Food Technology
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Näringslära

Nyckelord

Originalspråkengelska
Sidor (från-till)2518-23
Antal sidor6
TidskriftCancer Research
Volym41
Utgivningsnummer6
StatusPublished - 1981 jun
PublikationskategoriForskning
Peer review utfördJa