Effects of exposure to indoor nano-sized particles on heart rate variability

Forskningsoutput: Working paper


Airborne particles are associated with increased morbidity and mortality due to respiratory and cardiovascular diseases in polluted areas. There is a growing interest in fine particles with diameter < 100 nm and their potential health effects. Heart rate variability (HRV) is a noninvasive method for cardiovascular risk prediction in high prevalent groups.
Aim of study
To evaluate the impact of nano-sized indoor air particles on HRV.
All exposures were performed as controlled chamber experiments with particle exposure from burning candles, terpene+ozone-reactions or filtered air in a double-blind cross over fashion. 22 healthy females were investigated during 10 minute periods at different exposures and HRV were computed for various spectral components.
Heart rate was unchanged from baseline values in all groups during all experimental settings. Compared to filtered air, burning candle tended to decrease the power in both high (HF) and low (LF) spectral band but only in HF during terpene+ozone.
Exposure to nano-sized particles of burning candles or terpene+ozone seem to have an impact on heart rate variability, mediated by different aspects of autonomic cardiovascular control.
Practical implications
This study indicate that the HRV method may be used for information on physiological response of exposure different nano-sized particles and contribute to the understanding of mechanisms behind effects of particle exposures


Enheter & grupper

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Miljömedicin och yrkesmedicin


Antal sidor22
StatusUnpublished - 2011