Effects of oxygen therapy on wall-motion score index in patients with ST elevation myocardial infarction-the randomized SOCCER trial

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift


Background: Although oxygen (O2) is routinely used in patients with acute myocardial infarction (AMI), it may have negative effects. In this substudy of the SOCCER trial, we aimed to evaluate the effects of O2-treatment on myocardial function in patients with ST elevation myocardial infarction (STEMI). Methods: Normoxic (≥94%) STEMI patients were randomized in the ambulance to either supplemental O2 or room air until the end of the percutaneous coronary intervention (PCI). The patients underwent echocardiography on day 2-3 after the PCI and once again after 6 months. The study endpoints were wall-motion score index (WMSI) and left ventricular ejection fraction (LVEF). Results: Forty-six patients in the O2 group and 41 in the air group were included in the analysis. The index echocardiography showed no significant differences between the groups in WMSI (1.32±0.27 for O2 group vs 1.28±0.28 for air group) or LVEF (47.0±8.5% vs 49.2±8.1%). Nor were there differences at 6 months in WMSI (1.16±0.25 vs 1.14±0.24) or LVEF (53.5±5.8% vs 53.5±6.9%). Conclusion: The present findings indicate no harm or benefit of supplemental O2 on myocardial function in STEMI patients. Our results support that it is safe to withhold supplemental O2 in normoxic STEMI patients.


Enheter & grupper
Externa organisationer
  • Skåne University Hospital

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Kardiologi
  • Fysiologi
  • Annan klinisk medicin


Sidor (från-till)1130-1137
Antal sidor8
StatusPublished - 2017
Peer review utfördJa

Relaterad forskningsoutput

Ardavan Khoshnood, 2018 okt 19, I : BMC Emergency Medicine. 18, 35.

Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

Ardavan Khoshnood, Akbarzadeh, M., Marcus Carlsson, David Sparv, Bhiladvala, P., Mokhtari, A., David Erlinge & Ulf Ekelund, 2018, I : Scandinavian Cardiovascular Journal. 52, 2, s. 69-73 5 s.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Ardavan Khoshnood, Marcus Carlsson, Akbarzadeh, M., Bhiladvala, P., Roijer, A., David Nordlund, Höglund, P., Zughaft, D., Todorova, L., Arash Mokhtari, Håkan Arheden, David Erlinge & Ulf Ekelund, 2018, I : European Journal of Emergency Medicine. 25, 2, s. 78-84 7 s.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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Relaterade aktiviteter

Khoshnood, A. (Inbjuden talare)
2018 mar 9

Aktivitet: Föredrag eller presentationInbjuden talare

Khoshnood, A. (Talare)
2017 okt 26

Aktivitet: Föredrag eller presentationPresentation

Khoshnood, A. (presentatör)
2017 maj 19

Aktivitet: Föredrag eller presentationPresentation

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Ardavan Khoshnood (Mottagare), 2016

Priser och utmärkelser: Priser pch utmärkelserPris (inklusive medaljer och utmärkelser)

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