Emotional Awareness in Schizophrenia Is Associated With Gray Matter Volume of Right Precuneus

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Abstract

Objectives: We assessed the relationship between emotional awareness (e.g., the ability to identify and differentiate our own feelings and feelings of others) and regional brain volumes in healthy and in schizophrenia groups. Methods: Magnetic resonance images of 29 subjects with schizophrenia and 33 matched healthy controls were acquired. Brain gray matter was parcellated using FreeSurfer and 28 regions of interest associated with emotional awareness were analyzed. All participants were assessed using the Levels of Emotional Awareness Scale (LEAS) of Self and of Other. LEAS scores were correlated with gray matter volume for each hemisphere on the 14 brain regions of the emotional awareness network. Results: Individuals with schizophrenia showed decreased emotional awareness on both LEAS Self and LEAS Other compared to healthy controls. There were no statistically significant between-group differences in gray matter volumes of the emotional awareness network. The performance on LEAS Other correlated negatively with right precuneus gray matter volume only in the schizophrenia group. Conclusion: Our findings suggest a relationship between gray matter volume of the right precuneus and deficits in understanding of emotional states of others in schizophrenia.

Detaljer

Författare
  • Martin Jáni
  • Zora Kikinis
  • Jan Lošák
  • Ofer Pasternak
  • Filip Szczepankiewicz
  • Carina Heller
  • Sophia Swago
  • Annelise Silva
  • Sylvain Bouix
  • Marek Kubicki
  • Libor Ustohal
  • Petr Kudlička
  • Lubomír Vojtíšek
  • Carl Frederik Westin
  • Tomáš Kašpárek
Enheter & grupper
Externa organisationer
  • University Hospital Brno
  • Masaryk University
  • Harvard University
  • Universitätsklinikum Jena
  • Brigham and Women's Hospital, Boston
  • Friedrich Schiller University Jena
  • Boston Veteran's Administration (VA) Healthcare
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Psykiatri
  • Neurologi

Nyckelord

Originalspråkengelska
Artikelnummer601742
TidskriftFrontiers in Psychiatry
Volym12
StatusPublished - 2021
PublikationskategoriForskning
Peer review utfördJa