Enhanced and resumed GB virus C replication in HIV-1-infected individuals receiving HAART.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

In patients co-infected with HIV-1 and GB virus C (GBV-C), the disappearance of GBV-C RNA has been associated with accelerated disease progression. We studied longitudinal GBV-C viral titres in 28 HIV-1/GVB-C co-infected individuals receiving HAART. During HAART, median GBV-C RNA titres increased from 95 to 6000 copies/ml (P < 0.001). In patients interrupting HAART, GBV-C-RNA titres decreased as HIV replication resumed. These findings further support the theory that GBV-C replication could depend on the dynamics of HIV progression.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Infektionsmedicin
Originalspråkengelska
Sidor (från-till)1641-1643
TidskriftAIDS
Volym21
Utgivningsnummer12
StatusPublished - 2007
PublikationskategoriForskning
Peer review utfördJa