Expression Quantitative Trait Loci Acting Across Multiple Tissues Are Enriched in Inherited Risk for Coronary Artery Disease.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

-Despite recent discoveries of new genetic risk factors, the majority of risk for coronary artery disease (CAD) remains elusive. As the most proximal sensor of DNA variation, RNA abundance can help identify subpopulations of genetic variants active in and across tissues mediating CAD risk through gene expression.

Detaljer

Författare
  • Hassan Foroughi Asl
  • Husain A Talukdar
  • Alida S D Kindt
  • Rajeev K Jain
  • Raili Ermel
  • Arno Ruusalepp
  • Khanh-Dung H Nguyen
  • Radu Dobrin
  • Dermot F Reilly
  • Heribert Schunkert
  • Nilesh J Samani
  • Ingrid Brænne
  • Jeanette Erdmann
  • Olle Melander
  • Jianlong Qi
  • Torbjörn Ivert
  • Josefin Skogsberg
  • Eric E Schadt
  • Tom Michoel
  • Johan L M Björkegren
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Kardiologi
Originalspråkengelska
Sidor (från-till)305
TidskriftCirculation: Cardiovascular Genetics
Volym8
Utgåva nummer2
StatusPublished - 2015
PublikationskategoriForskning
Peer review utfördJa