Furanocoumarins with affinity to brain benzodiazepine receptors in vitro

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Eight furanocoumarins were isolated from a methanol extract of dried roots of Angelica dahurica. One of these, phellopterin, strongly (IC50 = 0.36 microM) inhibits the binding of [3H]diazepam to central nervous system benzodiazepine receptors in vitro, while the others, despite their structural similarities with phellopterin, are considerably less active.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Dermatologi och venereologi
Originalspråkengelska
Sidor (från-till)1121-1124
TidskriftPhytochemistry
Volym44
Utgåva nummer6
StatusPublished - 1997
PublikationskategoriForskning
Peer review utfördJa