Further important sensitizers in patients sensitive to fragrances - II. Reactivity to essential oils

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Further important sensitizers in patients sensitive to fragrances - II. Reactivity to essential oils. / Frosch, PJ; Johansen, JD; Menne, T; Pirker, C; Rastogi, SC; Andersen, KE; Bruze, Magnus; Goossens, A; Lepoittevin, JP; White, IR.

I: Contact Dermatitis, Vol. 47, Nr. 5, 2002, s. 279-287.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Harvard

Frosch, PJ, Johansen, JD, Menne, T, Pirker, C, Rastogi, SC, Andersen, KE, Bruze, M, Goossens, A, Lepoittevin, JP & White, IR 2002, 'Further important sensitizers in patients sensitive to fragrances - II. Reactivity to essential oils', Contact Dermatitis, vol. 47, nr. 5, s. 279-287. https://doi.org/10.1034/j.1600-0536.2002.470204.x

APA

Frosch, PJ., Johansen, JD., Menne, T., Pirker, C., Rastogi, SC., Andersen, KE., ... White, IR. (2002). Further important sensitizers in patients sensitive to fragrances - II. Reactivity to essential oils. Contact Dermatitis, 47(5), 279-287. https://doi.org/10.1034/j.1600-0536.2002.470204.x

CBE

Frosch PJ, Johansen JD, Menne T, Pirker C, Rastogi SC, Andersen KE, Bruze M, Goossens A, Lepoittevin JP, White IR. 2002. Further important sensitizers in patients sensitive to fragrances - II. Reactivity to essential oils. Contact Dermatitis. 47(5):279-287. https://doi.org/10.1034/j.1600-0536.2002.470204.x

MLA

Vancouver

Author

Frosch, PJ ; Johansen, JD ; Menne, T ; Pirker, C ; Rastogi, SC ; Andersen, KE ; Bruze, Magnus ; Goossens, A ; Lepoittevin, JP ; White, IR. / Further important sensitizers in patients sensitive to fragrances - II. Reactivity to essential oils. I: Contact Dermatitis. 2002 ; Vol. 47, Nr. 5. s. 279-287.

RIS

TY - JOUR

T1 - Further important sensitizers in patients sensitive to fragrances - II. Reactivity to essential oils

AU - Frosch, PJ

AU - Johansen, JD

AU - Menne, T

AU - Pirker, C

AU - Rastogi, SC

AU - Andersen, KE

AU - Bruze, Magnus

AU - Goossens, A

AU - Lepoittevin, JP

AU - White, IR

PY - 2002

Y1 - 2002

N2 - In order to find sensitizers additional to the current fragrance mix (FM) a series of fragrance materials (series II) was evaluated in 6 dermatological centres in Europe. 11 of the test materials were essential oils, the remaining 7 being either mixtures of isomers or simple chemicals of frequent usage in the perfume industry. 1606 patients were consecutively tested with series II and 8% FM. Each patient was classified regarding a history of adverse reactions to scented products: certain, probable, questionable, none. Reactions to FM occurred most frequently in 11.4% of the subjects. The 6 materials with the highest reactivity after the FM were ylang-ylang oil (YY) I (2.6%), YY II (2.5%), lemongrass oil (1.6%), narcissus absolute (1.3%), jasmine absolute (1.2%) and sandalwood oil (0.9%). 48 (3.0%) of the patients reacted only to materials of series II and not to FM. 6.0% of 1606 patients gave a history of adverse reactions to fragrances which was classified as certain. This group reacted to FM only in 22.9%, to series II and FM in 15.6% and to series II only in 5.2%. 63.5% of the patients reacting to both FM and 1 of the materials of series II had some type of positive fragrance history, which was higher in comparison to those with isolated reactions to FM (46.2% of 121) or to series II, respectively, (45.8% of 48). However, this difference was not statistically significant. In conclusion, the materials of series II identified a further subset of patients with a fragrance problem, which would have been missed by the current FM as the single screening tool for patch testing.

AB - In order to find sensitizers additional to the current fragrance mix (FM) a series of fragrance materials (series II) was evaluated in 6 dermatological centres in Europe. 11 of the test materials were essential oils, the remaining 7 being either mixtures of isomers or simple chemicals of frequent usage in the perfume industry. 1606 patients were consecutively tested with series II and 8% FM. Each patient was classified regarding a history of adverse reactions to scented products: certain, probable, questionable, none. Reactions to FM occurred most frequently in 11.4% of the subjects. The 6 materials with the highest reactivity after the FM were ylang-ylang oil (YY) I (2.6%), YY II (2.5%), lemongrass oil (1.6%), narcissus absolute (1.3%), jasmine absolute (1.2%) and sandalwood oil (0.9%). 48 (3.0%) of the patients reacted only to materials of series II and not to FM. 6.0% of 1606 patients gave a history of adverse reactions to fragrances which was classified as certain. This group reacted to FM only in 22.9%, to series II and FM in 15.6% and to series II only in 5.2%. 63.5% of the patients reacting to both FM and 1 of the materials of series II had some type of positive fragrance history, which was higher in comparison to those with isolated reactions to FM (46.2% of 121) or to series II, respectively, (45.8% of 48). However, this difference was not statistically significant. In conclusion, the materials of series II identified a further subset of patients with a fragrance problem, which would have been missed by the current FM as the single screening tool for patch testing.

KW - contact allergy

KW - essential oils

KW - fragrance mix

KW - fragrances

KW - history of

KW - patch testing

KW - fragrance sensitivity

U2 - 10.1034/j.1600-0536.2002.470204.x

DO - 10.1034/j.1600-0536.2002.470204.x

M3 - Article

VL - 47

SP - 279

EP - 287

JO - Contact Dermatitis

JF - Contact Dermatitis

SN - 0105-1873

IS - 5

ER -