Genome assembly, sex-biased gene expression and dosage compensation in the damselfly Ischnura elegans

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

The evolution of sex chromosomes, and patterns of sex-biased gene expression and dosage compensation, are poorly known among early winged insects such as odonates. We assembled and annotated the genome of Ischnura elegans (blue-tailed damselfly), which, like other odonates, has a male-hemigametic sex-determining system (X0 males, XX females). By identifying X-linked genes in I. elegans and their orthologs in other insect genomes, we found homologies between the X chromosome in odonates and chromosomes of other orders, including the X chromosome in Coleoptera. Next, we showed balanced expression of X-linked genes between sexes in adult I. elegans, i.e. evidence of dosage compensation. Finally, among the genes in the sex-determining pathway only fruitless was found to be X-linked, while only doublesex showed sex-biased expression. This study reveals partly conserved sex chromosome synteny and independent evolution of dosage compensation among insect orders separated by several hundred million years of evolutionary history.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • Catholic University of Leuven
  • Instituto de Ecología A.C.
  • The New Zealand Institute for Plant & Food Research Limited, Nelson, New Zealand
  • University of Auckland
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Genetik

Nyckelord

Originalspråkengelska
Sidor (från-till)1828-1837
Antal sidor10
TidskriftGenomics
Volym113
Utgåva nummer4
StatusPublished - 2021 jul 1
PublikationskategoriForskning
Peer review utfördJa