Gonococci cause immunosuppression by engaging a coinhibitory receptor on T lymphocytes

Forskningsoutput: TidskriftsbidragLetter

Abstract

Gonococci that bind the coinhibitory receptor CEACAM1 appear to down-regulate the activation and proliferation of CD4+ T cells. Such infection-induced immunosuppression helps explain why there is little specific immune response associated with gonococcal disease.

Detaljer

Författare
  • Staffan Normark
  • Barbara Albiger
  • Ann-Beth Jonsson
Externa organisationer
  • External Organization - Unknown
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Mikrobiologi inom det medicinska området
Originalspråkengelska
Sidor (från-till)210-211
TidskriftNature Immunology
Volym3
Utgåva nummer3
StatusPublished - 2002
PublikationskategoriForskning
Peer review utfördJa
Externt publiceradJa