Group A streptococci are protected from amoxicillin-mediated killing by vesicles containing β-lactamase derived from Haemophilus influenzae.

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Bibtex

@article{8cb8ac7fc2bd4059a0b6c1974cef8b5b,
title = "Group A streptococci are protected from amoxicillin-mediated killing by vesicles containing β-lactamase derived from Haemophilus influenzae.",
abstract = "Group A streptococci (GAS) cause, among other infections, pharyngotonsillitis in children. The species is frequently localized with the Gram-negative respiratory pathogens non-typeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis, which both produce outer membrane vesicles (OMVs). The aim of this study was to investigate whether OMVs isolated from NTHi contain functional β-lactamase and whether the OMVs hydrolyse amoxicillin and thus protect GAS from killing by the antibiotic.",
author = "Viveka Schaar and Ida Uddb{\"a}ck and Ther{\'e}se Nordstr{\"o}m and Kristian Riesbeck",
year = "2014",
doi = "10.1093/jac/dkt307",
language = "English",
volume = "69",
pages = "117--120",
journal = "Journal of Antimicrobial Chemotherapy",
issn = "1460-2091",
publisher = "Oxford University Press",
number = "1",

}