Hair as an indicator of the body content of polonium in humans: preliminary results from study of five male volunteers.

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Bibtex

@article{2225caaaf74b42a18b82dca0f7cc8df9,
title = "Hair as an indicator of the body content of polonium in humans: preliminary results from study of five male volunteers.",
abstract = "The radionuclide (210)Po is of importance from a radiation protection view and has properties that cause special problems when attempting to determine the body content in humans. Estimates have traditionally been made from either urine and/or fecal samples, which require a time-consuming radiochemical preparation before alpha spectrometric determination. In order to find a more simple and less labor intensive method hair has been used as a bioindicator and investigated in this study. The relationship between intake and excretion in hair has been estimated in five volunteers who ingested radioactive polonium ((209)Po as a bio-tracer for (210)Po) in well determined quantities. Four of the volunteers were given 5-10 Bq (209)Po in a single intake (acute intake) and one volunteer has ingested a daily intake of 58.7 mBq (209)Po for a period of 180 d. Human hair was found to reflect the daily clearance of ingested polonium peaking at 0.001-0.01% d(-1) of the ingested amount, thereafter decreasing mono-exponentially, corresponding to a biological half-time of 10-20 days. For the case of protracted intake a mono-exponential build-up was observed with a half-time of 40 ± 5 d. In addition, after cessation of intake, a short-term component (74%) with a biological half-time of 16 ± 4 d, and a long-term component (26%) with a half-time of 93 ± 53 d were observed. It is concluded that hair can be used to detect not only the amount of ingested polonium but also whether the intake was protracted or acute.",
author = "Christopher R{\"a}{\"a}f and Hanna Holstein and Elis Holm and P Roos",
year = "2015",
doi = "10.1016/j.jenvrad.2014.12.004",
language = "English",
volume = "141",
pages = "71--75",
journal = "Journal of Environmental Radioactivity",
issn = "1879-1700",
publisher = "Elsevier",

}