HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation.

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T1 - HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation.

AU - Al-Haidari, Amr

AU - Syk, Ingvar

AU - Thorlacius, Henrik

PY - 2014

Y1 - 2014

N2 - Simvastatin is widely used to lower cholesterol levels in patients with cardiovascular diseases, although accumulating evidence suggests that statins, such as simvastatin, also exert numerous anti-tumoral effects.

AB - Simvastatin is widely used to lower cholesterol levels in patients with cardiovascular diseases, although accumulating evidence suggests that statins, such as simvastatin, also exert numerous anti-tumoral effects.

U2 - 10.1016/j.bbrc.2014.02.078

DO - 10.1016/j.bbrc.2014.02.078

M3 - Article

VL - 446

SP - 68

EP - 72

JO - Biochemical and Biophysical Research Communications

T2 - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

SN - 1090-2104

IS - 1

ER -