Impact of surgical resection rate on survival in gastric cancer: nationwide study

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Impact of surgical resection rate on survival in gastric cancer : nationwide study. / Kung, C. H.; Jestin Hannan, C.; Linder, G.; Johansson, J.; Nilsson, M.; Hedberg, J.; Lindblad, M.

I: BJS Open, Vol. 5, Nr. 2, 2021.

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Kung, CH, Jestin Hannan, C, Linder, G, Johansson, J, Nilsson, M, Hedberg, J & Lindblad, M 2021, 'Impact of surgical resection rate on survival in gastric cancer: nationwide study', BJS Open, vol. 5, nr. 2. https://doi.org/10.1093/bjsopen/zraa017

APA

Kung, C. H., Jestin Hannan, C., Linder, G., Johansson, J., Nilsson, M., Hedberg, J., & Lindblad, M. (2021). Impact of surgical resection rate on survival in gastric cancer: nationwide study. BJS Open, 5(2). https://doi.org/10.1093/bjsopen/zraa017

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Kung, C. H. ; Jestin Hannan, C. ; Linder, G. ; Johansson, J. ; Nilsson, M. ; Hedberg, J. ; Lindblad, M. / Impact of surgical resection rate on survival in gastric cancer : nationwide study. I: BJS Open. 2021 ; Vol. 5, Nr. 2.

RIS

TY - JOUR

T1 - Impact of surgical resection rate on survival in gastric cancer

T2 - nationwide study

AU - Kung, C. H.

AU - Jestin Hannan, C.

AU - Linder, G.

AU - Johansson, J.

AU - Nilsson, M.

AU - Hedberg, J.

AU - Lindblad, M.

PY - 2021

Y1 - 2021

N2 - BACKGROUND: There are marked geographical variations in the proportion of patients undergoing resection for gastric cancer. This study investigated the impact of resection rate on survival. METHODS: All patients with potentially curable gastric cancer between 2006 and 2017 were identified from the Swedish National Register of Oesophageal and Gastric Cancer. The annual resection rate was calculated for each county per year. Resection rates in all counties for all years were grouped into tertiles and classified as low, intermediate or high. Survival was analysed using the Cox proportional hazards model. RESULTS: A total of 3465 patients were diagnosed with potentially curable gastric cancer, and 1934 (55.8 per cent) were resected. Resection rates in the low (1261 patients), intermediate (1141) and high (1063) tertiles were 0-50.0, 50.1-62.5 and 62.6-100 per cent respectively. The multivariable Cox analysis revealed better survival for patients diagnosed in counties during years with an intermediate versus low resection rate (hazard ratio (HR) 0.81, 95 per cent c.i. 0.74 to 0.90; P < 0.001) and high versus low resection rate (HR 0.80, 0.73 to 0.88; P < 0.001). CONCLUSION: This national register study showed large regional variation in resection rates for gastric cancer. A higher resection rate appeared to be beneficial with regard to overall survival for the entire population.

AB - BACKGROUND: There are marked geographical variations in the proportion of patients undergoing resection for gastric cancer. This study investigated the impact of resection rate on survival. METHODS: All patients with potentially curable gastric cancer between 2006 and 2017 were identified from the Swedish National Register of Oesophageal and Gastric Cancer. The annual resection rate was calculated for each county per year. Resection rates in all counties for all years were grouped into tertiles and classified as low, intermediate or high. Survival was analysed using the Cox proportional hazards model. RESULTS: A total of 3465 patients were diagnosed with potentially curable gastric cancer, and 1934 (55.8 per cent) were resected. Resection rates in the low (1261 patients), intermediate (1141) and high (1063) tertiles were 0-50.0, 50.1-62.5 and 62.6-100 per cent respectively. The multivariable Cox analysis revealed better survival for patients diagnosed in counties during years with an intermediate versus low resection rate (hazard ratio (HR) 0.81, 95 per cent c.i. 0.74 to 0.90; P < 0.001) and high versus low resection rate (HR 0.80, 0.73 to 0.88; P < 0.001). CONCLUSION: This national register study showed large regional variation in resection rates for gastric cancer. A higher resection rate appeared to be beneficial with regard to overall survival for the entire population.

U2 - 10.1093/bjsopen/zraa017

DO - 10.1093/bjsopen/zraa017

M3 - Article

C2 - 33688944

AN - SCOPUS:85102906783

VL - 5

JO - BJS Open

JF - BJS Open

SN - 2474-9842

IS - 2

ER -