Improved general and oral health in diabetic patients by an okinawan-based nordic diet: A pilot study

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Periodontal disease, periodontitis as well as the preceding gingivitis, has been associated with both obesity and diabetes. Studies have shown that diet changes can lead to a lower incidence of such inflammation. The aim of the present case series over four weeks was to study the effects on medical and dental conditions in patients with type 2 diabetes of the consumption of the Okinawan-based Nordic Diet (OBND®). Medical and dental examinations were performed to estimate the general health and gingivitis/periodontitis. Serum cytokine levels were assessed using Luminex technology. Eight of ten study participants completed the study. All participants lost weight (p = 0.012). Six out of seven that were treated with insulin could reduce their insulin intake after two weeks with OBND®. The reduction was about 16 units which corresponds to a 34% relative reduction compared to the starting point (range 15–63%). Fasting blood glucose values fell (p = 0.035). Hemoglobin A1c (HbA1c) (p = 0.01), triglycerides (p = 0.05), and low-density lipoprotein (LDL) (p = 0.05) were also reduced. Bleeding on probing changed from ~28% before any dietary changes to ~13% after two weeks with OBND® (p = 0.01). The reduction in gingival bleeding was as substantial as might be expected from one session of professional tooth cleaning. Markers of inflammation were also reduced. The OBND® thus showed significant promise in alleviating the impact of diabetes on dental as well as general health.

Detaljer

Författare
  • Helene Holmer
  • Cecilia Widén
  • Viveca Wallin Bengtsson
  • Michael Coleman
  • Björn Wohlfart
  • Stig Steen
  • Rutger Persson
  • Klas Sjöberg
Enheter & grupper
Externa organisationer
  • Central Hospital Kristianstad
  • Kristianstad University
  • Aston University
  • Skåne University Hospital
  • University of Washington
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Endokrinologi och diabetes
  • Odontologi

Nyckelord

Originalspråkengelska
Artikelnummer1949
TidskriftInternational Journal of Molecular Sciences
Volym19
Utgivningsnummer7
StatusPublished - 2018 jul 3
PublikationskategoriForskning
Peer review utfördJa