Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation.

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Bibtex

@article{86e7172d45c84b189965e143581136e9,
title = "Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation.",
abstract = "Exacerbations of asthma caused by respiratory viral infections are serious conditions in need of novel treatment. To this end animal models of asthma exacerbations are warranted. We have shown that dsRNA challenges or rhinoviral infection produce exacerbation effects in mice with ovalbumin (OVA)-induced allergic asthma. However, house dust mite (HDM) is a more human asthma-relevant allergen than OVA. We thus hypothesised that dsRNA challenges in mice with HDM-induced experimental asthma would produce important translational features of asthma exacerbations.",
author = "{Mahmutovic Persson}, Irma and Hamid Akbarshahi and Mandy Menzel and Angelica Brandelius and Lena Uller",
year = "2016",
doi = "10.1186/s12967-016-0808-x",
language = "English",
volume = "14",
journal = "Journal of Translational Medicine",
issn = "1479-5876",
publisher = "BioMed Central",
number = "1",

}