Indoor model simulation for covid-19 transport and exposure

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Transmission of respiratory viruses is a complex process involving emission, deposition in the airways, and infection. Inhalation is often the most relevant transmission mode in indoor environments. For severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the risk of inhalation transmission is not yet fully understood. Here, we used an indoor aerosol model combined with a regional inhaled deposited dose model to examine the indoor transport of aerosols from an infected person with novel coronavirus disease (COVID-19) to a susceptible person and assess the potential inhaled dose rate of particles. Two scenarios with different ventilation rates were compared, as well as adult female versus male recipients. Assuming a source strength of 10 viruses/s, in a tightly closed room with poor ventilation (0.5 h−1 ), the respiratory tract deposited dose rate was 140–350 and 100–260 inhaled viruses/hour for males and females; respectively. With ventilation at 3 h−1 the dose rate was only 30–90 viruses/hour. Correcting for the half-life of SARS-CoV-2 in air, these numbers are reduced by a factor of 1.2–2.2 for poorly ventilated rooms and 1.1–1.4 for well-ventilated rooms. Combined with future determinations of virus emission rates, the size distribution of aerosols containing the virus, and the infectious dose, these results could play an important role in understanding the full picture of potential inhalation transmission in indoor environments.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • University of Jordan
  • University of Helsinki
  • Helsinki University Central Hospital
  • King Saud bin Abdulaziz University for Health Sciences
  • University of Tartu
  • Nanjing University
  • Beijing University of Chemical Technology
  • Lomonosov Moscow State University
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Miljömedicin och yrkesmedicin
  • Infektionsmedicin

Nyckelord

Originalspråkengelska
Artikelnummer2927
Antal sidor16
TidskriftInternational Journal of Environmental Research and Public Health
Volym18
Utgåva nummer6
StatusPublished - 2021
PublikationskategoriForskning
Peer review utfördJa