Influence of androgen receptor repeat polymorphisms on personality traits in men

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Standard

Influence of androgen receptor repeat polymorphisms on personality traits in men. / Westberg, Lars; Henningsson, Susanne; Landen, Mikael; Annerbrink, Kristina; Melke, Jonas; Nilsson, Staffan; Rosmond, Roland; Holm, Goran; Anckarsäter, Henrik; Eriksson, Elias.

I: Journal of Psychiatry & Neuroscience, Vol. 34, Nr. 3, 2009, s. 205-213.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Harvard

Westberg, L, Henningsson, S, Landen, M, Annerbrink, K, Melke, J, Nilsson, S, Rosmond, R, Holm, G, Anckarsäter, H & Eriksson, E 2009, 'Influence of androgen receptor repeat polymorphisms on personality traits in men', Journal of Psychiatry & Neuroscience, vol. 34, nr. 3, s. 205-213.

APA

Westberg, L., Henningsson, S., Landen, M., Annerbrink, K., Melke, J., Nilsson, S., Rosmond, R., Holm, G., Anckarsäter, H., & Eriksson, E. (2009). Influence of androgen receptor repeat polymorphisms on personality traits in men. Journal of Psychiatry & Neuroscience, 34(3), 205-213.

CBE

Westberg L, Henningsson S, Landen M, Annerbrink K, Melke J, Nilsson S, Rosmond R, Holm G, Anckarsäter H, Eriksson E. 2009. Influence of androgen receptor repeat polymorphisms on personality traits in men. Journal of Psychiatry & Neuroscience. 34(3):205-213.

MLA

Vancouver

Westberg L, Henningsson S, Landen M, Annerbrink K, Melke J, Nilsson S et al. Influence of androgen receptor repeat polymorphisms on personality traits in men. Journal of Psychiatry & Neuroscience. 2009;34(3):205-213.

Author

Westberg, Lars ; Henningsson, Susanne ; Landen, Mikael ; Annerbrink, Kristina ; Melke, Jonas ; Nilsson, Staffan ; Rosmond, Roland ; Holm, Goran ; Anckarsäter, Henrik ; Eriksson, Elias. / Influence of androgen receptor repeat polymorphisms on personality traits in men. I: Journal of Psychiatry & Neuroscience. 2009 ; Vol. 34, Nr. 3. s. 205-213.

RIS

TY - JOUR

T1 - Influence of androgen receptor repeat polymorphisms on personality traits in men

AU - Westberg, Lars

AU - Henningsson, Susanne

AU - Landen, Mikael

AU - Annerbrink, Kristina

AU - Melke, Jonas

AU - Nilsson, Staffan

AU - Rosmond, Roland

AU - Holm, Goran

AU - Anckarsäter, Henrik

AU - Eriksson, Elias

PY - 2009

Y1 - 2009

N2 - Background: Testosterone has been attributed importance for various aspects of behaviour. The aim of our study was to investigate the potential influence of 2 functional polymorphisms in the amino terminal of the androgen receptor on personality traits in men. Methods: We assessed and genotyped 141 men born in 1944 recruited from the general population. We used 2 different instruments: the Karolinska Scales of Personality and the Temperament and Character Inventory. For replication, we similarly assessed 63 men recruited from a forensic psychiatry study group. Results: In the population-recruited sample, the lengths of the androgen receptor repeats were associated with neuroticism, extraversion and self-transcendence. The association with extraversion was replicated in the independent sample. Limitations: Our 2 samples differed in size; sample 1 was of moderate size and sample 2 was small. In addition, the homogeneity of sample 1 probably enhanced our ability to detect significant associations between genotype and phenotype. Conclusion: Our results suggest that the repeat polymorphisms in the androgen receptor gene may influence personality traits in men.

AB - Background: Testosterone has been attributed importance for various aspects of behaviour. The aim of our study was to investigate the potential influence of 2 functional polymorphisms in the amino terminal of the androgen receptor on personality traits in men. Methods: We assessed and genotyped 141 men born in 1944 recruited from the general population. We used 2 different instruments: the Karolinska Scales of Personality and the Temperament and Character Inventory. For replication, we similarly assessed 63 men recruited from a forensic psychiatry study group. Results: In the population-recruited sample, the lengths of the androgen receptor repeats were associated with neuroticism, extraversion and self-transcendence. The association with extraversion was replicated in the independent sample. Limitations: Our 2 samples differed in size; sample 1 was of moderate size and sample 2 was small. In addition, the homogeneity of sample 1 probably enhanced our ability to detect significant associations between genotype and phenotype. Conclusion: Our results suggest that the repeat polymorphisms in the androgen receptor gene may influence personality traits in men.

M3 - Article

VL - 34

SP - 205

EP - 213

JO - Journal of Psychiatry and Neuroscience

JF - Journal of Psychiatry and Neuroscience

SN - 1180-4882

IS - 3

ER -