iNOS affects matrix production in distal lung fibroblasts from patients with mild asthma.

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T1 - iNOS affects matrix production in distal lung fibroblasts from patients with mild asthma.

AU - Larsson Callerfelt, Anna-Karin

AU - Weitoft, Maria

AU - Nihlberg, Kristian

AU - Bjermer, Leif

AU - Westergren-Thorsson, Gunilla

AU - Tufvesson, Ellen

PY - 2015

Y1 - 2015

N2 - A high level of exhaled nitric oxide (NO) is a marker for inflammation in the airways of asthmatic subjects. However, little is known about how NO and inducible nitric oxides synthase (iNOS) activity may affect remodelling in the distal lung. We hypothesized that there is a link between iNOS and ongoing remodelling processes in the distal lung of mild asthmatics.

AB - A high level of exhaled nitric oxide (NO) is a marker for inflammation in the airways of asthmatic subjects. However, little is known about how NO and inducible nitric oxides synthase (iNOS) activity may affect remodelling in the distal lung. We hypothesized that there is a link between iNOS and ongoing remodelling processes in the distal lung of mild asthmatics.

U2 - 10.1016/j.pupt.2015.09.003

DO - 10.1016/j.pupt.2015.09.003

M3 - Review article

VL - 34

SP - 64

EP - 71

JO - Pulmonary Pharmacology and Therapeutics

T2 - Pulmonary Pharmacology and Therapeutics

JF - Pulmonary Pharmacology and Therapeutics

SN - 1522-9629

IS - sep 9

ER -